Friday, February 20, 2015

The Uncertain Gene - 11

You are Epigenetic: an overview
In the previous post of this series I said it's "probably the final post in this series".

But, Tom (who is a regular commenter here at Dredd Blog) brought up some new research concerning epigenetics (Tom's Comment).

Then, I kept thinking about the implications until it dawned on me that one aspect of the uncertain gene concept, elucidated upon in this series, is that proton tunnelling is also technically "epigenetic."

I mean that in the sense that any gene itself, in all genetic circumstances, does not "control" itself or anything else.

Thus Epigenetics, a discipline in and of itself, is a realm that studies what utilizes the genetic molecules, where those genetic molecules are utilized, when those molecules are utilized, how they are utilized, and why those molecules are utilized.

Thus, this is another case where nomenclature is paramount (Good Nomenclature: A Matter of Life and Death).

The papers that Tom alluded to concern valid epigenetic dynamics, because the nomenclature of Epigenetics covers all activity that acts upon gene molecules, including those that decide whether, for example, to turn the gene on or off:
Geneticists study the gene; however, for epigeneticists, there is no obvious 'epigene'. Nevertheless, during the past year, more than 2,500 articles, numerous scientific meetings and a new journal were devoted to the subject of epigenetics. It encompasses some of the most exciting contemporary biology and is portrayed by the popular press as a revolutionary new science — an antidote to the idea that we are hard-wired by our genes. So what is epigenetics? - (Perceptions of Epigenetics)

Much work has been published on the cis-regulatory elements that affect gene function locally, as well as on the biochemistry of the transcription factors and chromatin- and histone-modifying complexes that influence gene expression. However, surprisingly little information is available about how these components are organized within the three-dimensional space of the nucleus. Technological advances are now helping to identify the spatial relationships and interactions of genes and regulatory elements in the nucleus and are revealing an unexpectedly extensive network of communication within and between chromosomes [cf. this]. A crucial unresolved issue is the extent to which this organization affects gene function, rather than just reflecting it. - (Nuclear organization of the genome and the potential for gene regulation)

(see following link for more ...)
(Nature Insight: Epigenetics, Vol. 447, No. 7143 pp 396-440). The point is that epigenetic dynamics involve multiple levels of analysis and subsequent operations to, among other
Figure 1
things, eventually activate processes whereby the gene molecules and their analysis will eventually be handled in a customized way in the ribosome and/or ribozyme.

So, let's use the format of a layered graphic (see Figure 1 graphic to the right - click to enlarge) to assist in visualizing some of these known, and some of the yet unknown, dynamics involved.

Some of these epigenetic dynamics, as the concept relates to humans, are behavioral, including cultural behavior that impacts the individual.

IOW, the level of individual behavior is not controlled by gene molecules (see e.g. The "It's In Your Genes" Myth, 2; One Man's Junk Gene Is Another Man's Treasure Gene?, Microbial Hermeneutics - 3, On The Origin of Genieology, 2, 3).

Let's take a working example by asking: "how could these epigenetic operatives be having an impact?"

In the context of "answers" ... please notice some "puzzling" research ... that was considered in one prior Dredd Blog post:
From biology class to “C.S.I.,” we are told again and again that our genome is at the heart of our identity. Read the sequences in the chromosomes of a single cell, and learn everything about a person’s genetic information — or, as 23andme, a prominent genetic testing company, says on its Web site, “The more you know about your DNA, the more you know about yourself.”

But scientists are discovering that — to a surprising degree — we contain genetic multitudes. Not long ago, researchers had thought it was rare for the cells in a single healthy person to differ genetically in a significant way. But scientists are finding that it’s quite common for an individual to have multiple genomes. Some people, for example, have groups of cells with mutations that are not found in the rest of the body. Some have genomes that came from other people.

Medical researchers aren’t the only scientists interested in our multitudes of personal genomes. So are forensic scientists. When they attempt to identify criminals or murder victims by matching DNA, they want to avoid being misled by the variety of genomes inside a single person.

Last year, for example, forensic scientists at the Washington State Patrol Crime Laboratory Division described how a saliva sample and a sperm sample from the same suspect in a sexual assault case didn’t match.
(On The Origin of Genieology). The piece which Tom linked to, echoed the common misconception that "The human genome is the sequence of all the DNA on chromosomes. The [human] DNA is identical in every cell, from neurons to hearts to skin."

The (newly discovered) variant genetic material (whether RNA or DNA) existing within an individual, may be due to a proton tunnelling type of mutation (PTM); and/or a viral-microbial lateral gene transfer (LGT); and/or other layers or levels of epigenetic processes.

Which are symbolically depicted in Figure 1, and verbally described (at least in the abstract) in the scientific papers discussed above (Nature Insight: Epigenetics, Vol. 447, No. 7143 pp 396-440).

A lot of the lunacy that has manifested in the biological sciences, from Eugenics to The Selfish Gene myth of Dawkins, is due in whole or in part, to our scientific culture's failure to have a discipline I call "Abiology 101" (see Weekend Rebel Science Excursion - 27).

The extent of the impact of that failure is discussed in another Dredd Blog series (On the Origin of the Genes of Viruses, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12) and in previous posts of this series (The Uncertain Gene, 2, 3, 4, 5, 6, 7, 8, 9, 10).

The previous post in this series is here.

See if you can pick out some of the errors in this video, which is ~99% correct:



Thursday, February 19, 2015

The Rehabilitation of High Priest Bush II - 3

Oil-Qaeda Warlords Aplenty
This Oil-Qaeda bunch gives the word "progressive" new meaning.

They are progressing all right, or better said, they are all progressing to the right.

As usual, they are doing so with dire consequences for everyone except their Oil-Qaeda cohorts and minions.

They are among all of those in The Private Empire (MOMCOM: The Private Parts, 2, 3, 4, 5) who co-own the fleets and who send those fleets to Oilandia (The Fleets & Terrorism Follow The Oil - 5).

The Decider, also known as The High Priest In Chief, dimmed the lights of The Bushie Klan, by writing a letter to the French President explaining why he invaded Iraq:
The revelation this month in GQ magazine that Donald Rumsfeld as Defense Secretary embellished top-secret wartime memos with quotations from the Bible prompts a question. Why did he believe he could influence President
With God On Our Side
Bush by that means?

The answer may lie in an alarming story about George Bush’s Christian millenarian beliefs that has yet to come to light.

In 2003 while lobbying leaders to put together the Coalition of the Willing, President Bush spoke to France’s President Jacques Chirac. Bush wove a story about how the Biblical creatures Gog and Magog were at work in the Middle East and how they must be defeated.

In Genesis and Ezekiel Gog and Magog are forces of the Apocalypse who are prophesied to come out of the north and destroy Israel unless stopped. The Book of Revelation took up the Old Testament prophesy:
“And when the thousand years are expired, Satan shall be loosed out of his prison, And shall go out to deceive the nations which are in the four quarters of the earth, Gog and Magog, to gather them together to battle … and fire came down from God out of heaven, and devoured them.”
Bush believed the time had now come for that battle, telling Chirac:
“This confrontation is willed by God, who wants to use this conflict to erase his people’s enemies before a New Age begins”.
The story of the conversation emerged only because the Elysée Palace, baffled by Bush’s words, sought advice from Thomas Römer, a professor of
"Like, if you want my bro for preznit ..."
theology at the University of Lausanne. Four years later, Römer gave an account in the September 2007 issue of the university’s review, Allez savoir. The article apparently went unnoticed, although it was referred to in a French newspaper.

The story has now been confirmed by Chirac himself in a new book, published in France in March, by journalist Jean Claude Maurice. Chirac is said to have
Jeb's God is on Oil-Qaeda's Side
been stupefied and disturbed by Bush’s invocation of Biblical prophesy to justify the war in Iraq and “wondered how someone could be so superficial and fanatical in their beliefs”.

In the same year he spoke to Chirac, Bush had reportedly said to the Palestinian foreign minister that he was on “a mission from God” in launching the invasions of Iraq and Afghanistan and was receiving commands from the Lord.

There can be little doubt now that President Bush’s reason for launching the war in Iraq was, for him, fundamentally religious. He was driven by his belief that the attack on Saddam’s Iraq was the fulfilment of a Biblical prophesy in which he had been chosen to serve as the instrument of the Lord.
(Bush, God, Iraq and Gog, cf. The Dogma of The High Priest In Chief). Thus, as Dredd Blog surmised some years ago, there would need to be a rehabilitation movement in our future:
Some of you will remember that Dredd Blog saw this coming a while back:
Can you say "what Iraq war"?

The whole war episode may be played out after the fact as something that heroically saved the nation from a catastrophe caused by peak oil.

Especially "since all that pie in the sky lefty Al Gore green energy is a thousand years in the future".

The billboard sign of Bush II in Texas asking "Do you miss me yet" will take on a new meaning, and he may be seen as a hero who had the vision to save the nation.
(Iraq: World's Number One Oil Producer?). Jeb Bush can't run for president unless and until his Big Brother Bush II is seen in a better light.

MOMCOM is going to try to wash the brains of the people, yes, scrub them so hard that her favorite bushie will be loved by all once again.
(The Rehabilitation of High Priest Bush II, 2010, emphasis added). That expected future which not many would believe back about five years ago, in 2010, is here now isn't it?

How it turns out will be determined by the propaganda techniques developed by Oil-Qaeda experts in propaganda:
THE conscious and intelligent manipulation of the organized habits and opinions of the masses is an important element in democratic society. Those who manipulate this unseen mechanism of society constitute an invisible government which is the true ruling power of our country. We are governed, our minds are molded, our tastes formed, our ideas suggested, largely by men we have never heard of. This is a logical result of the way in which our democratic society is organized. Vast numbers of human beings must cooperate in this manner if they are to live together as a smoothly functioning society.

Our invisible governors are, in many cases, unaware of the identity of their fellow members in the inner cabinet.

They govern us by their qualities of natural leadership, their ability to supply needed ideas and by their key position in the social structure. Whatever attitude one chooses to take toward this condition, it remains a fact that in almost every act of our daily lives, whether in the sphere of politics or business, in our social conduct or our ethical thinking, we are dominated by the relatively small number of persons — a trifling fraction of our hundred and twenty [now 320] million — who understand the mental processes and social patterns of the masses. It is they who pull the wires which control the public mind, who harness old social forces and contrive new ways to bind and guide the world.
...
It is the purpose of this book to explain the structure of the mechanism which controls the public mind, and to tell how it is manipulated by the special pleader who seeks to create public acceptance for a particular idea or commodity. It will attempt at the same time to find the due place in the modern democratic scheme for this new propaganda and to suggest its gradually evolving code of ethics and practice.
(The Ways of Bernays, quoting American propagandist Bernays). At the moment the T-bagger arm of insanity is mounting the attack against Jebber The Whut because he is "too librul."

Go figure.

The previous post in this series is here.

"Pour some sugar on me ..." - Bill Maher (click the YouTube button lower right)



Sarah Barbie Bush: "I've chained my mind ..."



Wednesday, February 18, 2015

Civilization Is Now On Suicide Watch - 7

Insanity First:  a Nutter Tale
I. Introduction

As Dredd Blog has noted on occasion, and as have others, there are two ongoing activities of our cultures that are currently threatening the very existence of "civilization" (definition: What Do You Mean - World Civilization?, Confusing "Civilization" With "Species").

These, and any others that are validly related (e.g. The Criminally Insane Epoch: The Criminally Insane Epoch Arises) can be placed into the category "Sixth Mass Extinction" or "Anthropocene" (We Are Riding Out The Sixth Mass Extinction?).

This is considered to be "suicide" (see post title) or omnicide in the sense that it is or was preventable.

The Sixth Mass Extinction (6th Mass Extinction Documentation) began with the Industrial Revolution (The Death Juice of The Worried Revolution), followed some years later by the subsequent Petroleum Revolution (Petroleum Civilization: The Final Chapter (Confusing Life with Death)).

II. Two First Strikes (This is not baseball)

A. The First First Strike

It was the Petroleum Revolution that ended up being the First Strike in the war against the Earth's Life Systems (The Peak of Sanity - 3).

Many government reports, together with many scientific reports, indicate that if unabated, this environmental first strike has the power to destroy civilization (Government Climate Change Report, 2, 3, 4, 5, 6, 7, 8, 9).

It is already affecting millions of people around the globe, including some in the largest cities, in ways that are changing public planning already:
Climate change is already impacting New York City with rising temperatures
A rising sea floods all coastal cities
and sea levels, which will only worsen as the century continues, according to a report released Tuesday from a panel of scientific experts.

In its 2015 report, the New York City Panel on Climate Change found that the most populous city in the United States is expected to see more frequent heat waves and extreme precipitation events. This is in line with the national and international trends other leading scientific bodies have observed.

Projections [understimates] for sea level rise in New York City are 11 to 21 inches by the 2050s, 18 to 39 inches by the 2080s, and could reach as high as 6 feet by 2100.
(Sea Level Rise NYC, Annals of the New York Academy of Sciences). This is similar to Miami, Florida, which is already flooding too:
You don’t have to look 85 years into the future to see what a sinking world looks like—you only need to look as far as Miami.

Climate scientists have been warning the world about sea level rise for years, pleading with governments to cut back on carbon lest all our coastal cities go the way of Venice. In 2014, the Intergovernmental Panel on Climate Change released its fifth Assessment Report, predicting that oceans would rise more than 3 feet by 2100. Those projections make for some alarming visions of the future—cities water-logged, monuments submerged, islands created.
(Rising Sea Levels Are Already Making Miami’s Floods Worse). There are some projection photos, graphics, and "alarming visions" available (New Meaning Given to Deepwater Horizon).

B. The Second First Strike

The other First Strike is the initiation of nuclear war under the recent madness-engendered false belief that a nuclear war can be "won" (Civilization Is Now On Suicide Watch - 2).

The book "Striking First," depicted in the graphic at the top of today's post, as well as in this paper (Striking First, PDF), provide the general concept.

Historically, this was rejected by Bush I but was, not surprisingly, embraced by Bush II (cf. Bush Doctrine, Wolfowitz doctrine).

Surprisingly, to liberals anyway, the doctrine is also embraced by the Obama Administration (Obama Doctrine) with some modifications.

The Russians have picked up on this, and are being urged by their neoCons to implement the first strike dogma too (Russia Doctrine).

III. One Strike And You Are Out (this is not a game)

The ongoing environmental first strike is showing us that we have the power to destroy international cities, international ports, international infrastructure, international food ecosystems, international forest ecosystems, international ocean ecosystems, and the global climate system (we are already way into doing so).

In other words, we are at this moment actively destroying the things that make possible, and support, our global civilization.

Since this post is long enough already, I won't address why the Epigovernment and its government minions want to add another first strike (nuclear attack) to their death-wish list.

That must be left to the psychiatrists for now (but if you must read some psychoanalysis of it, see MOMCOM's Mass Suicide & Murder Pact - 5).

IV. Conclusion

Any individual or group doing this to themselves would be seen as wittingly or unwittingly killing themselves by way of a conscious or unconscious murder-suicide pact (MOMCOM's Mass Suicide & Murder Pact, 2, 3, 4, 5).

Our global culture, as well as our local cultures, can't seem to allow us to grasp that horrid notion.

That is because of the trances our cultures generate for us to grow up in, and to eventually make our own (Choose Your Trances Carefully, 2).

If only the only whores of civilization were simple male and female street walkers doing so because of their survival struggles during personal economic problems.

But, that unfortunately is not the case (The War Whores Ride The War Horse - 2).

The next post in this series is here, the previous post in this series is here.

Noam Chomsky addresses the issue:



Tuesday, February 17, 2015

The War Whores Ride The War Horse - 2

The "war is peace" trance is activating in the MSM.

The President, the Pope, and the Pentagon have said recently that global climate change is the greatest threat to national security (Blind Willie McTell News - 5).

The War Whore bosses over at MSNBC (e.g. Ed Show, Hardball, Morning Joe) freaked out.

Big Ed was going to do a thingy on the Gulf because of global warming (high in Australia today is 111F) induced climate change being more of a threat than terrorists (which made the amygdala of Ed's boss hog go hysterical).

So, War Whores, Spielberg's latest film (opens legs wide) is what the presstitute bosses at MSNBC are now doing instead (cf.  War is the Highway 61 of the 1%, Is War An Art or Is War A Disease?, The Goldilocks War Propaganda: Syria is Just Right, Another Spring of Whores of War).

Remember that their Johns invaded and destroyed Libya (MOMCOM And The Sins of Libya, 2) to bring it freedom (America’s Deadliest Export: Democracy), hence the mid-east curse "may the bushies bring you democracy."

Libya is the same country where the warmongers brought democracy and peace recently (before ISIS was created by propaganda and war); and it is that same place (except that now "it is all democratic and stuff") where ISIS is said to have just beheaded 25 Christians (which really pissed off General Jesus, a.k.a. "GJ", Hypothesis: The Cultural Amygdala - 4).

Other leg spreading sources are saying that the book about assholes (On The Origin of Assholes) is surging in sales in other countries that want their foggy streets to be heavily walked too (In the Fog of The Presstitutes, 2, 3).

GJ says those countries must wait in line, until after the peace generating bombing is done, before their souls get laid:
The Lord is a warrior and in Revelation 19 it says when he comes back, he's coming back as what? A warrior. A mighty warrior leading a mighty army, riding a white horse with a blood-stained white robe ... I believe that blood on that robe is the blood of his enemies 'cause he's coming back as a warrior carrying a sword.

And I believe now - I've checked this out - I believe that sword he'll be
"Jesus is coming with an AR-15" - U.S. General
carrying when he comes back is an AR-15.

Now I want you to think about this: where did the Second Amendment come from? ... From the Founding Fathers, it's in the Constitution. Well, yeah, I know that. But where did the whole concept come from? It came from Jesus when he said to his disciples 'now, if you don't have a sword, sell your cloak and buy one.'

I know, everybody says that was a metaphor. IT WAS NOT A METAPHOR! He was saying in building my kingdom, you're going to have to fight at times. You won't build my kingdom with a sword, but you're going to have to defend yourself. And that was the beginning of the Second Amendment, that's where the whole thing came from. I can't prove that historically and David [Barton] will counsel me when this is over, but I know that's where it came from.

And the sword today is an AR-15, so if you don't have one, go get one. You're supposed to have one. It's biblical.
(Gun-Toting Jesus Will Lead 'Mighty Army', emphasis added). Of course, GJ added that "patience is a virtue, so don't despair 'cause we will virtue the hell out of you in due time."

The previous post in this series is here.

Sgt. Ed Shultz's alter ego converts a ho mobile into a democratic dirt saving 'chine to level stuff for freedom:



Monday, February 16, 2015

Blind Willie McTell News - 5

Post @12/26/11
When I wrote the first post of this series years ago, it included a photo of Brian Williams.

He was no different than his peers in his McTell News reporting, in the sense that all of Main Stream Media (MSM) is a word and picture machine designed to put a cultural patina in place.

The MSM is like play-pretend for little kids ("Thankfully, kids are hardwired to play pretend. In fact, in a recent Motherboard Moms poll nearly 75 percent of moms said their preschoolers engage in make-believe activities every day." -Let's Play Pretend!, Parents dot com) who become sentient within an existing, controlling, guiding culture.

Little kids become adults who will have grown up to become far more sophisticated with their cognitive play pretend machinations than they were as children (The Matriarch of The Matrix, 2, 3).

Dredd Blog has pointed out for a long time that the MSM is a vast multi-billion dollar industry designed to keep us play pretending about what our culture really is, and is doing (The Deceit Business).

And that is why citizens who want to know what is in the matrix must choose (Choose Your Trances Carefully).

The MSM lackies are reading from an Epigovernment generated cold war script lately, because the terrorist-propaganda trance they generated is weakening:
The original falsehood behind the Iraq War was that Saddam Hussein had weapons of mass destruction and intended to use them against America either directly or by giving them to al-Qaeda. The opening lie about the Ukraine crisis was that Russian President Vladimir Putin instigated the conflict as part of some Hitlerian plan to conquer much of Europe.

Yet, while the Hussein-WMD claim was hard for the common citizen to assess because it was supposedly supported by U.S. intelligence information that was kept secret, the Putin-Ukraine lie collapses under the most cursory examination based simply of what’s publicly known and what makes sense.

Nevertheless, the New York Times – much as it did when it was falsely reporting breathlessly about “aluminum tubes” for Iraq’s non-existent nuclear weapons program – continues to promote U.S. government propaganda about Ukraine as fact and dismisses any rational assessment of the situation as crazy.

On Friday, the Times concluded its lead editorial with the assertion that: “What remains incontrovertible is that Ukraine is Mr. Putin’s war.” But the point is anything but “incontrovertible.” Indeed, the crisis was most certainly not instigated by Putin.

The actually “incontrovertible” facts about the Ukraine crisis are these: The destabilization of President Viktor Yanukovych’s elected government began in November 2013 when Yanukovych balked at a proposed association agreement promoted by the European Union. He sought more time after the sticker shock of learning from Kiev economic experts that the deal would cost Ukraine $160 billion in lost revenue by cutting trade with Russia.

It was German Chancellor Angela Merkel [goaded by other NATO/EU/US leaders], not Vladimir Putin, who pushed the EU agreement and miscalculated the consequences, as the German newsmagazine Der Spiegel has reported. Putin’s only role in that time frame was to offer a more generous $15 billion aid package to Ukraine, not exactly a war-like act.
(The Putin-Did-It Conspiracy Theory). Furthermore, the President indicated, in his State of the Union Speech to Congress (SOTU), that the Pentagon had informed him that the greatest threat to national security is global warming induced climate change.

Thus, Pentagon military scientists are in accord with 97% of civilian climate scientists (Has The Navy Fallen For The Greatest Hoax?) as are the courts (Have Courts Fallen For The Greatest Hoax?).

Nevertheless, Brian Williams @ McTell News put on just about 25 minutes of news about climate change in the past year (see video below), compared to hundreds of hours of news about terrorism being the greatest threat.

In other words, "majoring in the minors" as it were:
It seems climate change remains one potentially world-shattering issue that just can't get any respect on television. No Sunday morning show except MSNBC's "Up" so much as mentioned climate change, or the march, save for one stray reference on "This Week" by The Nation's Katrina vanden Heuvel. She pointed out that the march was actually gathering right outside the ABC studios in Lincoln Center where the show is taped.

"NBC Nightly News" was the only evening news show to do any segment on the march. (ABC devoted about 23 seconds to the topic in its evening show, and CBS spent exactly zero seconds on it.) Cable news, with the exception of Al Jazeera America, mostly looked the other way, besides a couple of segments on CNN and MSNBC.
(Huffington Post, cf. this, this, and this). Let's face it, this is the denial behavior of a suicide-murder cult (MOMCOM's Mass Suicide & Murder Pact, 2, 3, 4, 5).

The next post in this series is here, the previous post in this series is here.

Real Time with Bill Maher @2:30: "NBC news spent 25 minutes all year on the most important issue of our time ... this is journalistic malpractice" (25 min. per yr. is about 1/2 of 1% of weekday evening news time):