Thursday, August 17, 2023

Small Brains Considered - 15

Where da atoms at?

I. Size Matters

It was noted in the Chimera Detection series recently that one of the ways chimera develop is through natural processes (Chimera Detection, 2, 3);

For example, noting that the "Central Dogma of Molecular Biology" is that RNA comes from DNA", then also noting that mRNA is produced in the cell's nucleus by transcription, then further along amino acids and proteins are made using that mRNA instruction kit and atoms (Central Dogma).

What that means is that the atomic makeup of DNA is changed to RNA and on to amino acids and proteins by natural genetic processes including "cognition" by the tiniest of brains.

The appendices show that those tiniest of brains are composed mostly of 4 atom types (Appendices: Human, Microbe, SARS-CoV-2, and Toxo). 

The appendices have a common look and feel even though one is RNA focused and the others are DNA focused.

Each diagnostic set begins with a "Full-Genome" HTML table, followed by two "Tatabox" sections..

It shows counts of all nucleotide in the GenBank genome that it is linked to.

That Full-Genome section is followed by a "Tatabox" section of the full genome, which has a count of the nucleotides in that section of the genome, as well as an 'N' count for that section.
    
Finally there is a "Clean Tatabox" counts table section which contains, among other things, the number of 'chimera' in the aforesaid Tatabox (the clean tatabox nucleotide count plus the clean tatabox chimera nucleotide count  equals the total tatabox nucleotide count.
    
All of those tables also detail the atomic structure involved by listing the Carbon, Hydrogen, Nitrogen, and Oxygen atom counts in the nucleotides in the section involved.

At the bottom of each table is a "Totals" column which is the total number of atoms in that section of the genome ("Atom Count" column).

Each atom's total ("Atom Count" column) divided by the total count of all atoms ("Totals" column) derives the "Percent" value in the last column ("Percent" column).

II. What The Scientists Say

According to the scientists in the first videos below (Dr. Bassler), ninety-eight or so percent of our DNA/RNA is microbial (non-human).

But more than that, our DNA/RNA as well as the microbial DNA/RNA is composed primarily of four atom types (Carbon, Nitrogen, Hydrogen, and Oxygen).

Today's five appendices are based on an analysis of modern and ancient chromosomes in the GenBank, various microbial genomes in the GenBank, and some virus genomes in the GenBank.

All of them have URL links to their GenBank location where the FASTA format genomes were acquired for this post and its appendices.

Compared to DNA, RNA has a lower carbon atom ratio (4 to 4.75), hydrogen (2 to 3.75), and nitrogen atom ratio (4 to 5.25),  but a higher oxygen ratio (2 to 1). So the 32/35/25/6 does not hold for RNA because DNA has Thymine but RNA has Uracil.

So the RNA tables and the DNA tables vary some in terms of percentages (mostly in the hydrogen percent).

After all, it boils down to atomic structure, and when that is the same in bacteria, other single celled organisms, humans, and animals, it raises questions as to the brains of the organization. (i.e. cognition).

Especially the size of the brains and where the brain begins and ends (Atom Size).

So how do geneticists and forensic scientists tell the difference when analyzing the DNA and RNA in genomes?

Where does it come from, seeing as how atoms existed before cellular genomes did.

Well, "we don't know" is the answer in the second video below (Dr. Falkowski).

III. What Mystical Scientists Say

Other scientists have gone rogue from their previous scientific explanations to now say that 'micro-tubules' in atomic structure is where the brain essence is, including afterlife, rebirth, and other mystical ideologies (Small Brains Considered - 7).

Perhaps it is because they have no answers or "we don't know" because the machines existed before us:

"I have even done so to the point that I now encourage more scientific textbooks with the title "Abiology 101" in addition to and in contrast with "Biology 101" (see e.g. Did Abiotic Intelligence Precede Biotic Intelligence?, Putting A Face On Machine Mutation - 3)."

(Weekend Rebel Science Excursion - 27). I dig rebels with a good cause ('good trouble').

IV. Size Still Matters

Why, then, should we ignore the size of time that took place prior to the time that carbon 'emerged' from 'short-lived, hot, boom boom stars' long after the 'bigga badda boom' is said to have 'taken place'?

That was when the physical universe was reported to be non-living 'machines' (The New Paradigm: The Physical Universe Is Mostly Machine - 2). 

Small machines must make functional brains eh?

The next post in this series is here, the previous post in this series is here.





2 comments:

  1. "Chimeric Sequences

    Submitters will be contacted regarding sequences identified as chimeric. Chimeras are artifact sequences formed by two or more biological sequences incorrectly joined together. This often occurs during PCR reactions using mixed templates (i.e., uncultured environmental samples). Incomplete extensions during PCR allow subsequent PCR cycles to use a partially extended strand to bind to the template of a different, but similar, sequence. This partially extended strand then acts as a primer to extend and form a chimeric sequence. Once created, the chimeric sequence is then further amplified in subsequent cycles. The end result is a PCR artifact that does not represent a sequence that exists in nature.

    Studies have estimated that as many as 30% of the sequences from mixed template environmental samples may be chimeric. While chimera formation is most common in mixed template amplifications, in practice it is also seen at lower frequency in supposedly pure cultures." (Link)

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  2. "Where da atoms at?" The word 'atom' is not mentioned in the Wikipedia Tata box entry (Wikipedia TATA box).

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