Friday, January 3, 2014

Weekend Rebel Science Excursion - 26

Dr. James Hansen "rewarded" for truth telling
In the previous post we rebelliously took a look at the "scientific" madness around "dark matter" in physics.

In another post we took a look at the same incompetent "scientific" ideology concerning "dark matter" in genetics (The Uncertain Gene - 3).

Obviously, "dark matter" is the "scientific" way to bloviate about the unknown, a form of primal beating the chest to signal "we got this" when "we don't got this."

Today, let's focus on the Human Genome Project with its pants down, an example of the failure of a moth of scientific endeavor that flew too close, with wings of imagination, to the flame of reality, thus crashed and burned.

The video at the bottom of today's post is of a President of the United States who should have been talking about our map of human genes within the context of "dark matter", but instead he was sabotaged by ignorance and ended up calling ignorance enlightenment (he along with millions of other folks).

To cut to the chase, notice that human genes are less "big dog" than was expected at that time:
There was nothing extraordinary about the Japanese canopy plant — that is, until Pellicer analyzed the stained cells using flow cytometry, a high-throughput technique to detect features of cells suspended in liquid. To Pellicer’s eye, the balls of DNA inside P. japonica’s nuclei looked “really, really big,” he recalls. Soon, he confirmed that P. japonica carries the largest known eukaryotic genome on the planet, with a whopping 150 billion base pairs — 50 times the size of the human genome. “We were astonished,” says Pellicer. Plants in general are known to have sizable genomes, often as a result of whole-genome duplications, so “we were expecting to find big genomes, but nothing that big.”
(The Scientist, Genomes Gone Wild, emphasis added). That "feeling of surprise" was explained more "succinctly" in another place, as pointed out in a previous Dredd Blog post:
The Human Genome Project’s most startling finding was that human genes, as currently defined, make up less than 2 percent of all the DNA on the genome, and that the total number of genes is relatively small. Scientists had predicted there might be 80,000 to 140,000 human genes, but the current tally is fewer than 25,000 — as one scientific paper put it, SOMEWHERE BETWEEN that of A CHICKEN AND A GRAPE. The remaining 98 percent of our DNA, once dismissed as “junk DNA,” is now taken more seriously. Researchers have focused on introns, in the gaps between the coding segments of genes, which may play a crucial role in regulating gene expression, by switching them on and off in response to environmental stimuli.
(One Man's Junk Gene Is Another Man's Treasure Gene?, emphasis added). This would not be all that unexpected to the famous evolutionist Dr. Ernst Mayr.

Dr. Mayr is the one who famously said that human intelligence is a lethal mutation (What Kind of Intelligence Is A Lethal Mutation?).

I am reminded once again that DNA is a molecular machine, i.e. it is not alive (Putting A Face On Machine Mutation - 4).

I am also reminded that our cells, therefore our selves, are also composed of machines, molecular machines (The New Paradigm: The Physical Universe Is Mostly Machine) wrapped in a capsid of organic flesh a la cyborgs.

The evolution of machines also comes to mind (ibid).

Have a good weekend!

The previous post in this series is here.

Concerning the human genome, called "the map" by President Clinton:
President Clinton was sabotaged by his speech writers who were sabotaged by genetic scientists who were in the "dark matter" about genetics, but who did not know it.
Thus, they misled President Clinton, resulting in his misinformed official declaration about a map with very little, if anything, on it:
"Without a doubt this is the most important most wondrous map ever produced by humankind."
Little wonder, then, that any such map is in The W Direction.

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