|Any Way The Wind Blows|
On HighWay 61
In the previous post of this series I compared the "original SARS-CoV-2 virus" from Wuhan, China to one of its more recent versions, "the Omicron Variant" (On The Origin Of The Home Of COVID-19 - 29).
That comparison "a million American deaths" after the original appeared, was not about whether or not the virus kills.
Today's appendices contain relatively recent genomes from various countries.
These appendices have a similar design compared to the appendices in the previous post, however, I have added additional tables in today's appendices.
The process for developing the data shown in the appendices is explained in the MIT video at the end of this post, so "use it or lose it".
II. Comparison Tables
An extra comparison table is provided specifically to compare each non-Wuhan version of the virus to the Wuhan version, for the specific purpose of detecting substantial changes (not trivial changes).
I have also added a "Count Table" which provides the number of codons in the Wuhan version compared to number of codons in each non-Wuhan version (from around the globe).
In this Count Table there are 51 viruses listed, only 3 of which are 'malformed':
Wuhan count: 71 (Malaysia/MYS/MT372480.1) count: 45
Wuhan count: 71 (East Timor/TLS/MT641766.1) count: 45
Wuhan count: 71 (Argentina/ARG/MW553295.1) count: 69
(3÷51 = 0.058823529, or ~5.9%). There are several reasons malformation or a new formation may take place (e.g.):
1) technicians improperly collected otherwise good samples,
2) technicians were given bad samples,
3) chemicals damaged the host cell causing chimeric hosts and/or viruses,
4) proton tunneling caused a mutation,
5) natural change took place.
The overall result depicted in the appendices is the same as in the previous post, in the sense that there is no substantial difference between the Wuhan version and these non-Wuhan versions in most cases.
The "take-home" shown in them is that the SARS-CoV-2 virus genome is not substantially variable.
Over a million people have died in the USA, and millions more around the globe, even though there has been no substantial change in the substantial portion of the virus that I can detect yet ("once a killer virus, always a killer virus?").
In future posts I am going to do a date sequence comparison from an SQL database that has close to 50,000 FASTA files in it.
IV. Menu of Appendices
Here is a menu of today's appendices for your perusal:
V. Closing Comments
I recommend that you use the Count Table first, notice any mismatches in numbers, and then look-up the country it applies to in the Countries menu appendix which applies.
Load that Countries menu appendix and peruse the codons, amino acids, and atom counts for the malformed virus to see how the Wuhan original SARS-CoV-2 virus compares to the more recent later SARS-CoV-2 virus discovered in that country.
The "Wuhan Codon Sequence Compared To Subsequent Codons" HTML table (following the "Codons, Amino Acids and Chemical Formulas" HTML table) contains a link to the GenBank data of the Wuhan virus as well as a link to the more recent SARS-CoV-2 virus it is being compared to.
How the virus mRNA codons & amino acids are extracted from the genome: