Friday, April 1, 2022

Dredd Is Required To Resist Gram-negative Bacterial Infection

Dredd Blog
The Dredd
Gene
is atomic

Dredd Blog has used the notions of memetics from "day one" (The Memes of Penrose; The Toxic Bridge To Everywhere; A Structure RE: Corruption of Memes).

In a quote below, the "father" of the U.S. Constitution uses "meme-speak" when he calls war a "germ" that generates more "germs".

Check it out, because during cognitive pandemics a special meme is given heightened consideration:

"vaccime

(pron. vak-seem) Any meta-meme which confers resistance or immunity to one or more memes, allowing that person to be exposed without acquiring an active infection ... Common [vaccimes] are "Faith", "Loyalty", "Skepticism", and "tolerance" ... Every [meme complex] includes a vaccime to protect against rival memes."

 (The Memetic Lexicon). This type of discourse in conversations is, meme or not, genetic and atomic.

Memetically speaking, regular readers may know that microbiologists have determined that the Dredd gene enhances the immune system of readers:

"We have isolated loss-of-function mutations in the caspase encoding gene dredd, which block the expression of all genes that code for peptides with antibacterial activity. These mutations also render [targets of memes] highly susceptible to infection by Gram-negative bacteria. Our results demonstrate that Dredd regulates antibacterial peptide gene expression, and we propose that Dredd ... is required to resist Gram-negative bacterial infections.

(Dredd is required to resist Gram-negative bacterial infection, a published scientific paper, emphasis memes added). Now let's get down to brass tacks.

The Dredd Gene gives readers an advantage over the war germ

"Of all the enemies to public liberty war is, perhaps, the most to be dreaded, because it comprises and develops the germ of every other.

War is the parent of armies; from these proceed debts and taxes; and armies, and debts, and taxes are the known instruments for bringing the many under the domination of the few. In war, too, the discretionary power of the Executive is extended; its influence in dealing out offices, honors, and emoluments is multiplied: and all the means of seducing the minds, are added to those of subduing the force, of the people.

The same malignant aspect in republicanism may be traced in the inequality of fortunes, and the opportunities of fraud, growing out of a state of war, and in the degeneracy of manners and of morals, engendered by both.

No nation could preserve its freedom in the midst of continual warfare.

Those truths are well established."

 (American Feudalism; Extinction: Peace, emphasis added). The war germ projection comes along with The Dredd Gene package.

The Dredd Gene is described in scientific detail in a GenBank file:

VERSION  [GenBank identity] AE014298.5           

            ...
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     /note="Dredd-RD; Dmel\Dredd-RD; CG7486-RD; Dmel\CG7486-RD"
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     /note="Dredd-RE; Dmel\Dredd-RE; CG7486-RE; Dmel\CG7486-RE"
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     /note="Dredd-RF; Dmel\Dredd-RF; CG7486-RF; Dmel\CG7486-RF"
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     /note="Dredd-RG; Dmel\Dredd-RG; CG7486-RG; Dmel\CG7486-RG"
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     CG7486-PD; Dredd-PD; death-related ced-3/neural precursor
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     CG7486-PE; Dredd-PE; death-related ced-3/neural precursor
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
                     CG7486-PG; Dredd-PG; death-related ced-3/neural precursor
                     /gene="Dredd"
                     /gene_synonym="dcp-2/dredd"
                     /gene_synonym="Dcp-2/Dredd"
                     /gene_synonym="dDredd"
                     /gene_synonym="dredd"
                     /gene_synonym="Dredd/DCP-2"
            ...

(Dredd Gene, chromosome X, after the file loads, use "CTRL F" to search for "Dredd"). It's science doods and doodettes!

Happy onion day.


Doggies R us ...



Wednesday, March 30, 2022

Antarctica 2.0 - 13

Fig. 1 Areas/Sectors of Antarctica

The graphs in today's post illustrate what has been repeated from time to time in this series (Antarctica 2.0, 2, 3, 4, 5, 6 [& supplements A, B, C, D, E, F], 7, 8, 9, 10, 11, 12). 

To begin with, the Sahara desert receives more precipitation per square mile than Antarctica, the Earth's largest desert, does.

Many textbooks were written before those factors were known, so they set forth erroneous factors and figures.

Those errors in textbooks and published papers led to various myths about Antarctica, which are still being perpetuated by some in one sector of the media (The Warming Science Commentariat, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15).

The whole picture (all Areas/Sectors) is depicted in the graphic at Fig. 1.

The individual areas/sectors (A,B,C,D,E,F) are graphed at Fig. 2 - Fig. 7 (Area/Sector D, Amundsen Sea, is not graphed due to a data download problem).

Fig. 2 All Antarctica

The basic theme of all of the graphs presented today is to contrast the glacial "ice-melt temperature" (temperature at which the ice in contact with seawater will melt) and the ambient seawater temperature (seawater temperature at various depth levels where the seawater is in contact with the glacial ice).

There are three graph lines representing the temperature (TEOS-10 Conservative Temperature) at three depth levels (Epipelagic, Mesopelagic, and Bathypelagic).

The "take-home" information these graphs present is that the deeper seawater all around Antarctica, where tidewater glaciers flow into the ocean, is warmer than the ice it is in contact with or is close to (Quantum Oceanography, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16).

Fig. 3 Area/Sector A
Many performers in "The Warming Commentariat" have been "looking for love in all the wrong places" by focusing on the surface above sea level while ignoring the vast current that flows deep in the seas of Antarctica (The Ghost Plumes, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15;The Ghost Photons, 2, 3).
Fig. 4 Area/Sector B

The grounding lines of tidewater glaciers are not limited to West Antarctica, instead, the extent of tidewater glacier grounding lines reaches all around the perimeter of Antarctica along the coastline:

"This is a significant factor in terms of sea level change because the warmer waters, which are above (warmer than) the ice-melt temperature, are in contact with tens of thousands of kilometers (~58,000 km) of glacial ice."

(The Way of Civilizations - 2). We must remember that The Industrial Revolution of circa 1750 has been causing global warming, at an accelerating rate, all around the globe.

Fig. 5 Area/Sector C
Some 93% of that solar heat, trapped by green house gases, ends up in the world's oceans.

Eventually that "ocean heat" even reaches the deep waters surrounding Antarctica  (In Search Of Ocean Heat, 2, 3, 4, 5, 6, 7, 8, 9, 10).

There it is hidden from The Warming Commentariat because that realm "majors in the minors" (and will likely continue to use "worse than previously thought", "surprise", and more) during seemingly endless placation episodes (which are even contaminating some scientists):

Fig. 6 Area/Sector E

"Peter Neff, a glaciologist and assistant research professor at the University of Minnesota, said that to see even a small ice shelf collapse in East Antarctica was a surprise."

(Entire Conger ice shelf has collapsed in [East] Antarctica). A "small collapse" (in Fig. 1 Area/Sector B) is a major surprise within the realm of the denialists.

"Surprise" and "worse than previously thought" will continue to roll off the tongues, flow from the ink-pens, and click-bait out from the keyboards within the realm of our "criminal" denialists:

Fig. 7 Area/Sector F

"Today's IPCC report is an atlas of human suffering and a damning indictment of failed climate leadership. With fact upon fact, this report reveals how people and the planet are getting clobbered by climate change. Nearly half of humanity is living in the danger zone – now.  Many ecosystems are at the point of no return – now. Unchecked carbon pollution is forcing the world's most vulnerable on a frog march to destruction – now. The facts are undeniable. This abdication of leadership is criminal."

(How Microbes Communicate In The Tiniest Language - 3). Even the tiny microbes are better at warning their own species of pending danger than our Warming Commentariat.

In closing, remember that Conger Glacier is just down the trail from Totten Glacier, which I mentioned a few years back:

"I am talking about the main trail that leads to the plume of "the doomsday glacier" and its big brother the Totten Glacier."

(In Pursuit of Plume Theory). Totten is in a neighborhood that can supply a heavy dose of seaport problems (Hot, Warm, & Cold Thermal Facts: Tidewater-Glaciers - 2).

Totten Glacier (Conger Glacier's neighbor) itself can cause a catastrophe:

"Totten Glacier, East Antarctica, a glacier that holds a 3.9 m [12.8 ft] sea level change equivalent"

(Widespread Grounding Line Retreat of Totten Glacier, East Antarctica, Over the 21st Century).

The next post in this series is here, the previous post in this series is here.